New PDF release: Advances in Topical Antifungal Therapy

By R. J. Hay (auth.), R. J. Hay MD, MRCP, MRCPath. (eds.)

ISBN-10: 3540173021

ISBN-13: 9783540173021

ISBN-10: 3642717179

ISBN-13: 9783642717178

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Extra resources for Advances in Topical Antifungal Therapy

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0003) . 'vluIHlII ANOVA I 10..... ll~" II 'Jill,. ')l1I 101 rklllllm",or tlrH) 8J IpI Illlu4IfIIllltllnl rIr 11 VII III " I '0',,1111' ft' f)(M,,),! ''' U""I 111111 Ilnrl N(Jlhhrif' (I,-OO()OJ) Fig. 2. Clinical improvement of candidosis after start of treatment assessment of therapeutic results (Fig. 3) 2 weeks after the termination of treatment. The outcome was rated as "very good" in 90% of patients treated with bifonazole, 73% of patients treated with Ircolm nl J very good Bifonazole - 27 9()

4, 5] favourable findings were obtained with bifonazole in rosacea and seborrhoeic 29 dermatitis. Besides the substance's antimicrobial activity, antiinflammatory properties of bifonazole could be responsible for these effects. The assumption that bifanazole has anti-inflammatory activity is supported by various experimental studies on animals [7,8,9]. A substance-specific inhibitory effect on keratinase, an enzyme inducing inflammation, may play an essential role here. This was reported by Abbink (this volume).

Note the contrast between the background and the fungus and the septa of the hyphae (x 1000) Fig. 2. Mycelial elements and yeasts in smears from vulvovaginal candidosis (x 270) Fig. 3. Trichophton rubrum infection of the glabrous skin 35 Incidental occurrence of textile fibres was easily distinguished from fungal elements because the fibres were evenly stained and without septa. Discussion The sampling technique using tape is basically the same as that used for the sampling of microcultures, which is a technique for safer and quicker culture diagnoses [2, 3, 4].

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Advances in Topical Antifungal Therapy by R. J. Hay (auth.), R. J. Hay MD, MRCP, MRCPath. (eds.)


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